EGF (Epidermal Growth Factor)
A skin conditioning peptide ingredient listed in EU cosmetic databases—often used in repair & renewal formulas.
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✨ real molecule sketch
Spotted this on a label?
Oligopeptide-1
That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.
Structure (cute edition)
✨ real molecule sketch
Lab-made growth factor (oligopeptide-1)—a longer message molecule; we show a simplified chain here.
INCI: SH-OLIGOPEPTIDE-1 · ~6 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
Knowledge base: scientific article published on 01 April 2019
PubMed: 474 indexed papers (search PubMed)
- Intersection of Pediatric Hypertension and Cardiovascular-Kidney-Metabolic Disease. · Current hypertension reports
- Functions of Uninflatable in the Drosophila melanogaster wing and notum. · PloS one
- Early-onset drusen in Malattia Leventinese with EFEMP1 mutation differ from drusen in age-related macular degeneration. · Romanian journal of ophthalmology
- Secretory autophagy mediates SLC16A3/MCT4-dependent lactate secretion to drive metastatic progression in triple-negative breast cancer. · Autophagy
- Dietary Sodium-Regulated Plasma SVEP1 and Inverse Salt Sensitivity. · Hypertension (Dallas, Tex. : 1979)
- Fibroblast-Derived Microfibrillar-Associated Protein 5 Exerts Cardioprotective Effects After Myocardial Infarction by Activating the NOTCH2 Signaling in Cardiomyocytes. · Journal of the American Heart Association
- The Role of Vitamin D in Retinal Physiology. · Romanian journal of ophthalmology
- Toward the development of an innovative pharmacological compound employing peptides for EGFR-mediated drug delivery in anaplastic thyroid carcinoma. · Biochemical pharmacology
Clinical trials: 2415 studies on ClinicalTrials.gov (view search)
- TIP in Patients Affected by Metastatic TNBC · UNKNOWN
- MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer. · COMPLETED
- Observational Study of Afatinib 30 mg Daily · UNKNOWN
- Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer · UNKNOWN
- The Molecular Epidemiology of Epidermal Growth Factor Receptor (EGFR) Mutations in Patients With Advanced EGFR Mutation-positive Non-small Cell Lung Cancer Treated With Afatinib · COMPLETED
- ELBA: Exemestane and Lapatinib in Advanced Breast Cancer · WITHDRAWN
- Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer · RECRUITING
- A Study for CTC Expression and cfDNA/RNA Assessment in Metastatic Breast Cancer Patients · RECRUITING
ChEMBL: NERVE GROWTH FACTOR · max phase 2.0
What brands say it does
Sh-oligopeptide-1 EU CosIng describes it as: sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.
Where you’ll find it
Recovery serums, post-treatment creams, and premium anti-aging formulas. Look for Sh-oligopeptide-1 on the INCI list.
Other names you might see
Oligopeptide-1
sh-Oligopeptide-1
Sh-oligopeptide-1
Where to buy
Real purchase links from Sephora, Ulta, Target, and Amazon — typical prices $20.00–$29.00.
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Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.