EGF (Epidermal Growth Factor)
A buzzy "growth factor" ingredient in high-end serums—popular in K-beauty and clinic-style brands.
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✨ real molecule sketch
Spotted this on a label?
Oligopeptide-1
That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.
Structure (cute edition)
✨ real molecule sketch
Lab-made growth factor (oligopeptide-1)—a longer message molecule; we show a simplified chain here.
INCI: SH-OLIGOPEPTIDE-1 · ~6 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
Knowledge base: scientific article published on 01 April 2019
PubMed: 473 indexed papers (search PubMed)
- Functions of Uninflatable in the Drosophila melanogaster wing and notum. · PloS one
- Early-onset drusen in Malattia Leventinese with EFEMP1 mutation differ from drusen in age-related macular degeneration. · Romanian journal of ophthalmology
- Secretory autophagy mediates SLC16A3/MCT4-dependent lactate secretion to drive metastatic progression in triple-negative breast cancer. · Autophagy
- Dietary Sodium-Regulated Plasma SVEP1 and Inverse Salt Sensitivity. · Hypertension (Dallas, Tex. : 1979)
- Fibroblast-Derived Microfibrillar-Associated Protein 5 Exerts Cardioprotective Effects After Myocardial Infarction by Activating the NOTCH2 Signaling in Cardiomyocytes. · Journal of the American Heart Association
- The Role of Vitamin D in Retinal Physiology. · Romanian journal of ophthalmology
- Toward the development of an innovative pharmacological compound employing peptides for EGFR-mediated drug delivery in anaplastic thyroid carcinoma. · Biochemical pharmacology
- In vitro and in vivo validation studies of optimized iron oxide nanoparticles carrying targeting ligands for a new therapeutic strategy in head and neck cancers. · Nanoscale advances
Clinical trials: 2398 studies on ClinicalTrials.gov (view search)
- Pre-operation Chemo and Antibody Therapy Followed by Surgical Resection and Adjuvant Chemoradiation for Gastric Cancer · COMPLETED
- Efficacy Evaluation of TCI153 Probiotics for Skin Beautification · COMPLETED
- Dasatinib In Combination With Trastuzumab And Paclitaxel In First Line Treatment Of Her2-Positive MBC Patients · COMPLETED
- Tyrosine Kinase Inhibitors in Metastastic Adenoid Cystic Carcinoma · RECRUITING
- Multispectral Bimodal Fluorescence Guided Surgery of High-grade Glioma With Cetuximab-800CW and 5-ALA (5-aminolevulinic Acid) · UNKNOWN
- Sym004 in Combination With FOLFIRI in Metastatic Colorectal Cancer Patients · TERMINATED
- Her2-positive Lung Cancer Treated With Dedicated Drug · COMPLETED
- Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of SCT200 in Patients With Advanced Solid Tumors · UNKNOWN
ChEMBL: NERVE GROWTH FACTOR · max phase 2.0
What brands say it does
EGF in skin care refers to lab-made growth factors that brands claim help skin renew itself faster and recover from dryness or irritation. It is one of the more talked-about ingredients online; quality and concentration vary a lot between products.
Where you’ll find it
Premium serums, post-treatment recovery products, and "glass skin" routines.
Other names you might see
Oligopeptide-1
sh-Oligopeptide-1
Sh-oligopeptide-1
Where to buy
Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.
Compare with similar peptides
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Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.