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✨ real molecule sketch
Spotted this on a label?
Palmitoyl Pentapeptide-4
That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.
Structure (cute edition)
✨ real molecule sketch
Five amino acids linked together, with a palmitic acid tail—signal-peptide style, meant to nudge collagen chatter in skin.
INCI: PALMITOYL PENTAPEPTIDE-4 · ~5 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
Knowledge base: chemical compound — Wikipedia
PubMed: 11 indexed papers (search PubMed)
- Synergistic Effects of Injectable Platelet-Rich Fibrin and Bioactive Peptides on Dermal Fibroblast Viability and Extracellular Matrix Gene Expression: An In Vitro Study. · Molecules (Basel, Switzerland)
- Self-Assembly and Wound Healing Activity of Biomimetic Cycloalkane-Based Lipopeptides. · ACS applied materials & interfaces
- Boosting Cosmeceutical Peptides: Coupling Imidazolium-Based Ionic Liquids to Pentapeptide-4 Originates New Leads with Antimicrobial and Collagenesis-Inducing Activities. · Microbiology spectrum
- Matrixyl Patch vs Matrixyl Cream: A Comparative In Vivo Investigation of Matrixyl (MTI) Effect on Wound Healing. · ACS omega
- The Effects of a Novel Series of KTTKS Analogues on Cytotoxicity and Proteolytic Activity. · Molecules (Basel, Switzerland)
- N-Terminal Acetylation and C-Terminal Amidation of Spirulina platensis-Derived Hexapeptide: Anti-Photoaging Activity and Proteomic Analysis. · Marine drugs
- Turning a Collagenesis-Inducing Peptide Into a Potent Antibacterial and Antibiofilm Agent Against Multidrug-Resistant Gram-Negative Bacteria. · Frontiers in microbiology
- Self-Assembly, Tunable Hydrogel Properties, and Selective Anti-Cancer Activity of a Carnosine-Derived Lipidated Peptide. · ACS applied materials & interfaces
ChEMBL: CHEMBL1159980
What brands say it does
Matrixyl is a synthetic peptide blend often described as helping skin look plumper and fine lines less noticeable. It works quietly in the background—think of it as an ingredient brands add to support collagen-related messaging in the formula, not a quick fix.
Where you’ll find it
Moisturizers, serums, and eye creams—especially products labeled for wrinkles or loss of firmness.
Other names you might see
Palmitoyl Pentapeptide-4
Matrixyl 3000
Where to buy
Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.
Compare with similar peptides
Similar peptides
Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.