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Pentapeptide-22

A skin conditioning peptide ingredient listed in EU cosmetic databases—often used in anti-aging formulas.

Pentapeptide-22 illustration
Reading ingredients on a skincare label

Spotted this on a label?

Pentapeptide-22

That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.

Structure (cute edition)

Simplified amino acid chain for Pentapeptide-22

Pentapeptide-22 is the synthetic peptide consisting of arginine, glycine and tryptophan.

INCI: PENTAPEPTIDE-22 · ~5 amino acids in our simplified view

Research & public records

Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.

ChEMBL: CHEMBL1159980

What brands say it does

Pentapeptide-22 EU CosIng describes it as: Pentapeptide-22 is the synthetic peptide consisting of arginine, glycine and tryptophan.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.

Where you’ll find it

Anti-aging serums, moisturizers, and multi-peptide complexes. Look for Pentapeptide-22 on the INCI list.

Other names you might see

Pentapeptide-22

Where to buy

Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.

Peptide Skinjection™ Peptide-Infused Face & Eye Tape for Wrinkles and Aging Skin
Peter Thomas Roth

Peptide Skinjection™ Peptide-Infused Face & Eye Tape for Wrinkles and Aging Skin

$36.00 · ★ 4.8529

Shop at Sephora →
Tomato Firming Serum
BYROE

Tomato Firming Serum

$85.00

Shop at Ulta →

Similar peptides

Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.