Sh-polypeptide-1
A skin conditioning peptide ingredient listed in EU cosmetic databases—often used in repair & renewal formulas.
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Spotted this on a label?
Sh-polypeptide-1
That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.
Structure (cute edition)
sh-Polypeptide-1 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Basic Fibroblast Growth Factor used as such or adapted to the production host. It contains a maximum of 288 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
INCI: SH-POLYPEPTIDE-1 · ~2 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
ChEMBL: CHEMBL4299330
What brands say it does
Sh-polypeptide-1 EU CosIng describes it as: sh-Polypeptide-1 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Basic Fibroblast Growth Factor used as such or adapted to the production host. It contains a maximum of 288 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.
Where you’ll find it
Recovery serums, post-treatment creams, and premium anti-aging formulas. Look for Sh-polypeptide-1 on the INCI list.
Other names you might see
Sh-polypeptide-1
Where to buy
Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.
Compare with similar peptides
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Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.