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Sh-polypeptide-57

A skin protecting peptide ingredient listed in EU cosmetic databases—often used in repair & renewal formulas.

Sh-polypeptide-57 illustration
Reading ingredients on a skincare label

Spotted this on a label?

Sh-polypeptide-57

That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.

Structure (cute edition)

Simplified amino acid chain for Sh-polypeptide-57

Beta-Peptide,P4HB,Prolyl 4 Hydroxylase.

INCI: SH-POLYPEPTIDE-57 · ~12 amino acids in our simplified view

Research & public records

Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.

ChEMBL: CHEMBL4299330

What brands say it does

Sh-polypeptide-57 EU CosIng describes it as: Beta-Peptide,P4HB,Prolyl 4 Hydroxylase.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.

Where you’ll find it

Recovery serums, post-treatment creams, and premium anti-aging formulas. Look for Sh-polypeptide-57 on the INCI list.

Other names you might see

Sh-polypeptide-57

Where to buy

Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.

Protini Polypeptide Firming Moisturizer
Drunk Elephant

Protini Polypeptide Firming Moisturizer

$24.00 - $99.00 · ★ 4.5

Shop at Ulta →
Resurrection Polypeptide Cream
cocokind

Resurrection Polypeptide Cream

$26.99 · ★ 4.7

Shop at Ulta →
Calm Movements Eye & Cheek Mask
Superegg

Calm Movements Eye & Cheek Mask

$50.00

Shop at Ulta →
Instant Angel Lipid-Rich Firming Moisturizer
Dieux

Instant Angel Lipid-Rich Firming Moisturizer

$25.00 - $45.00 · ★ 4.544

Shop at Sephora →
LightBoost Eye Cream
Solawave

LightBoost Eye Cream

$44.00 · ★ 4.8

Shop at Ulta →
LightBoost Face & Neck Rich Cream
Solawave

LightBoost Face & Neck Rich Cream

$52.00 · ★ 4.8

Shop at Ulta →
No.9 NAD+ Collagen Under Eye Patch
numbuzin

No.9 NAD+ Collagen Under Eye Patch

$15.00

Shop at Ulta →

Similar peptides

Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.