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Tetrapeptide-49

A skin conditioning peptide ingredient listed in EU cosmetic databases—often used in anti-aging formulas.

Tetrapeptide-49 illustration
Reading ingredients on a skincare label

Spotted this on a label?

Tetrapeptide-49

That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.

Structure (cute edition)

Simplified amino acid chain for Tetrapeptide-49

Tetrapeptide-49 is the synthetic peptide consisting of arginine, phenylalanine, and tyrosine.

INCI: TETRAPEPTIDE-49 · ~4 amino acids in our simplified view

Research & public records

Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.

ChEMBL: CHEMBL3659217

What brands say it does

Tetrapeptide-49 EU CosIng describes it as: Tetrapeptide-49 is the synthetic peptide consisting of arginine, phenylalanine, and tyrosine.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.

Where you’ll find it

Anti-aging serums, moisturizers, and multi-peptide complexes. Look for Tetrapeptide-49 on the INCI list.

Other names you might see

Tetrapeptide-49

Similar peptides

Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.