Tetrapeptide-81
A skin conditioning emollient peptide ingredient listed in EU cosmetic databases—often used in anti-aging formulas.
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Spotted this on a label?
Tetrapeptide-81
That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.
Structure (cute edition)
Tetrapeptide-81 is the synthetic peptide consisting of glycine, leucine and phenylalanine.
INCI: TETRAPEPTIDE-81 · ~4 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
ChEMBL: CHEMBL3666912
What brands say it does
Tetrapeptide-81 EU CosIng describes it as: Tetrapeptide-81 is the synthetic peptide consisting of glycine, leucine and phenylalanine.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.
Where you’ll find it
Anti-aging serums, moisturizers, and multi-peptide complexes. Look for Tetrapeptide-81 on the INCI list.
Other names you might see
Tetrapeptide-81
Where to buy
Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.
Similar peptides
Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.