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Cyclo Hexapeptide-120

A hair conditioning, hair fixing, skin conditioning humectant peptide ingredient listed in EU cosmetic databases—often used in expression lines formulas.

Cyclo Hexapeptide-120 illustration
Reading ingredients on a skincare label

Spotted this on a label?

Cyclo Hexapeptide-120

That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.

Structure (cute edition)

Simplified amino acid chain for Cyclo Hexapeptide-120

Cyclo Hexapeptide-120 is the peptide consisting of cyclized Hexapeptide-120.

INCI: CYCLO HEXAPEPTIDE-120 · ~6 amino acids in our simplified view

Research & public records

Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.

ChEMBL: CHEMBL109185

What brands say it does

Cyclo Hexapeptide-120 EU CosIng describes it as: Cyclo Hexapeptide-120 is the peptide consisting of cyclized Hexapeptide-120.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.

Where you’ll find it

Forehead serums, smile-line treatments, and peptide "line softening" products. Look for Cyclo Hexapeptide-120 on the INCI list.

Other names you might see

Cyclo Hexapeptide-120

Where to buy

Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.

Auracle Peptide & Antioxidant Smooth + Depuff  Eye Serum
Dieux

Auracle Peptide & Antioxidant Smooth + Depuff Eye Serum

$44.00 · ★ 4.605

Shop at Sephora →

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Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.