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Heptapeptide-59

A skin conditioning miscellaneous peptide ingredient listed in EU cosmetic databases—often used in expression lines formulas.

Heptapeptide-59 illustration
Reading ingredients on a skincare label

Spotted this on a label?

Heptapeptide-59

That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.

Structure (cute edition)

Simplified amino acid chain for Heptapeptide-59

Heptapeptide-59 is the synthetic peptide consisting of arginine and lysine.

INCI: HEPTAPEPTIDE-59 · ~7 amino acids in our simplified view

Research & public records

Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.

ChEMBL: POLYMYXIN B HEPTAPEPTIDE

What brands say it does

Heptapeptide-59 EU CosIng describes it as: Heptapeptide-59 is the synthetic peptide consisting of arginine and lysine.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.

Where you’ll find it

Forehead serums, smile-line treatments, and peptide "line softening" products. Look for Heptapeptide-59 on the INCI list.

Other names you might see

Heptapeptide-59

Where to buy

Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.

DOUBLE SERUM Age-Defying Concentrate
Clarins

DOUBLE SERUM Age-Defying Concentrate

$95.00 - $190.00 · ★ 4.5

Shop at Ulta →
DOUBLE SERUM Eye Firming & Hydrating Concentrate
Clarins

DOUBLE SERUM Eye Firming & Hydrating Concentrate

$84.00 · ★ 4.3

Shop at Ulta →
DOUBLE SERUM Light Texture
Clarins

DOUBLE SERUM Light Texture

$95.00 - $140.00 · ★ 4.5

Shop at Ulta →
Instant Angel Lipid-Rich Firming Moisturizer
Dieux

Instant Angel Lipid-Rich Firming Moisturizer

$25.00 - $45.00 · ★ 4.544

Shop at Sephora →
Niacinamide Serum 12% Plus Zinc 2%
Naturium

Niacinamide Serum 12% Plus Zinc 2%

$16.99 · ★ 4.5

Shop at Ulta →
SUPERCHARGED Serum 2.0 Electrolyte Enriched Activated Treatment
FOREO

SUPERCHARGED Serum 2.0 Electrolyte Enriched Activated Treatment

$59.00 · ★ 4.7

Shop at Ulta →
Expert PDRN Caffeine Shot Serum for Puffiness
IOPE

Expert PDRN Caffeine Shot Serum for Puffiness

$43.00 · ★ 4.7632

Shop at Sephora →

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Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.