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Hexapeptide-65

A antioxidant, skin protecting peptide ingredient listed in EU cosmetic databases—often used in expression lines formulas.

Hexapeptide-65 illustration
Reading ingredients on a skincare label

Spotted this on a label?

Hexapeptide-65

That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.

Structure (cute edition)

Simplified amino acid chain for Hexapeptide-65

Hexapeptide-65 is the synthetic peptide consisting of alanine, lysine and proline.

INCI: HEXAPEPTIDE-65 · ~6 amino acids in our simplified view

Research & public records

Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.

ChEMBL: CHEMBL109185

What brands say it does

Hexapeptide-65 EU CosIng describes it as: Hexapeptide-65 is the synthetic peptide consisting of alanine, lysine and proline.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.

Where you’ll find it

Forehead serums, smile-line treatments, and peptide "line softening" products. Look for Hexapeptide-65 on the INCI list.

Other names you might see

Hexapeptide-65

Similar peptides

Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.