Back to all peptides

Hexapeptide-80

A skin conditioning miscellaneous peptide ingredient listed in EU cosmetic databases—often used in expression lines formulas.

Hexapeptide-80 illustration
Reading ingredients on a skincare label

Spotted this on a label?

Hexapeptide-80

That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.

Structure (cute edition)

Simplified amino acid chain for Hexapeptide-80

Hexapeptide-80 is the synthetic peptide consisting of alanine and glycine.

INCI: HEXAPEPTIDE-80 · ~6 amino acids in our simplified view

Research & public records

Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.

ChEMBL: CHEMBL109185

What brands say it does

Hexapeptide-80 EU CosIng describes it as: Hexapeptide-80 is the synthetic peptide consisting of alanine and glycine.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.

Where you’ll find it

Forehead serums, smile-line treatments, and peptide "line softening" products. Look for Hexapeptide-80 on the INCI list.

Other names you might see

Hexapeptide-80

Where to buy

Real purchase links from Sephora, Ulta, Target, and Amazon — tap a product to check price and buy.

Clinique Smart Clinical Repair Wrinkle Correcting Serum
Clinique

Clinique Smart Clinical Repair Wrinkle Correcting Serum

$80.00 - $192.00 · ★ 4.4

Shop at Ulta →
Cryo + Soothing Hydrogel Mask
Rael

Cryo + Soothing Hydrogel Mask

$4.99 - $18.99 · ★ 5

Shop at Ulta →
I Am Sheet Mask
TONYMOLY

I Am Sheet Mask

$3.75 · ★ 4.3

Shop at Ulta →
PDRN Exosome Skinplaning Glaze Mask with Collagen & Peptide
COSRX

PDRN Exosome Skinplaning Glaze Mask with Collagen & Peptide

$17.00 · ★ 4.8

Shop at Ulta →
Smart Clinical Repair Overnight Recovery Face Cream + Mask
Clinique

Smart Clinical Repair Overnight Recovery Face Cream + Mask

$80.00 · ★ 4.6

Shop at Ulta →

Similar peptides

Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.