Tetrapeptide-53
A skin conditioning peptide ingredient listed in EU cosmetic databases—often used in eyes formulas.
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Spotted this on a label?
Tetrapeptide-53
That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.
Structure (cute edition)
Tetrapeptide-53 is the synthetic peptide consisting of isoleucine, phenylalanine and tyrosine.
INCI: TETRAPEPTIDE-53 · ~4 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
ChEMBL: CHEMBL3645627
What brands say it does
Tetrapeptide-53 EU CosIng describes it as: Tetrapeptide-53 is the synthetic peptide consisting of isoleucine, phenylalanine and tyrosine.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.
Where you’ll find it
Eye creams, depuffing gels, and brightening treatments. Look for Tetrapeptide-53 on the INCI list.
Other names you might see
Tetrapeptide-53
Compare with similar peptides
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Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.