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Tripeptide-48

A anti-sebum, skin protecting peptide ingredient listed in EU cosmetic databases—often used in oil control formulas.

Tripeptide-48 illustration
Reading ingredients on a skincare label

Spotted this on a label?

Tripeptide-48

That’s the INCI name—the official way it appears on the back of your serum or cream. Same ingredient, different marketing names.

Structure (cute edition)

Simplified amino acid chain for Tripeptide-48

Tripeptide-48 is a synthetic peptide consisting of histidine, leucine and valine.

INCI: TRIPEPTIDE-48 · ~3 amino acids in our simplified view

Research & public records

Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.

ChEMBL: MACROCYCLIC TRIPEPTIDE MOTIF

What brands say it does

Tripeptide-48 EU CosIng describes it as: Tripeptide-48 is a synthetic peptide consisting of histidine, leucine and valine.. In skin care it is typically a supporting active—meant to complement hydrators and antioxidants rather than work alone.

Where you’ll find it

Balancing serums and lightweight moisturizers for oily or blemish-prone skin. Look for Tripeptide-48 on the INCI list.

Other names you might see

Tripeptide-48

Compare with similar peptides

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Educational only—not medical advice. Results vary; talk to a dermatologist for personal recommendations.